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Article: Volume 45 Number 10 Page 952 - November 2018

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  Dent Update 2018; 45: 952-960

Oral medicine:  Oral Manifestations of Secondary Hyperparathyroidism: A Case Report and Literature Review

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Abstract: A 52-year-old male with secondary hyperparathyroidism resulting from polycystic kidney disease, undergoing dialysis for 18 years, is documented. The case showed radiographic mandibular bilateral osteolytic lesions with ground glass appearance, diminished lamina dura, maxillary horizontal bone loss, but no maxillofacial expansion. Additionally, cases of hyperparathyroidism are reviewed to associate oral radiographic features with disease severity. The review suggests that in secondary hyperparathyroidism: 1) jaw demineralization, lamina dura loss, and osteolytic lesions occur with varying consistency depending on disease stage; 2) there is no gender predilection of oral manifestation occurrence; and 3) with advancing age, lamina dura changes may occur with increasing frequency.

Clinical relevance: This article discusses the oral radiographic signs and symptoms that present in patients with secondary hyperparathyroidism.

Author notes: Jordan Cheng, DMD, Faculty of Dentistry, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada V6T 1Z3.

Objective: To appreciate the appearance and prevalence of oral and radiographic manifestations and appropriate treatment guidelines of secondary hyperparathyroidism which may occur as a result of chronic kidney disease.

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