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References

Paul K, Islam A, Volponi AA. Future horizons: embedding the evolving science of regenerative dentistry in a modern, sustainable dental curriculum. Br Dent J. 2022; 232:207-210
Li Y, Duan X, Chen Y Dental stem cell-derived extracellular vesicles as promising therapeutic agents in the treatment of diseases. Int J Oral Sci. 2022; 14 https://doi.org/10.1038/s41368-021-00152-2
Srijaya T C, Sriram S, Sugii S, Kasim N H A. Stem cells in dentistry: potential applications and perspectives in clinical research. In: Pham P (ed.). Cham, Switzerland: Springer; 2016
Soudi A, Yazdanian M, Ranjbar R Role and application of stem cells in dental regeneration: a comprehensive overview. EXCLI J. 2021; 20:454-489
Zeitlin BD. Banking on teeth – stem cells and the dental office. Biomed J. 2020; 43:124-133 https://doi.org/10.1016/j.bj.2020.02.003

Stem cell therapy in dentistry: the future for oral tissue regeneration

From Volume 51, Issue 1, January 2024 | Page 67

Authors

Enis Veseli

Department of Prosthodontics, Dental School, Faculty of Medicine, University of Pristina, Pristina, Kosovo

Articles by Enis Veseli

Article

In the last period in medicine, including the field of dentistry, extensive research has been conducted on the regenerative ability of stem cells. Currently, therapies for oral health diseases can permit certain clinical parameters during the diagnosis and development of diseases, but cannot regenerate lost tissue. In light of this, researchers are increasingly interested in achieving proper regeneration of lost dental tissues as technology develops.1

Dental-related stem cells are attractive sources of mesenchymal stem/stromal cells (MSCs), which can be isolated from the dental pulp, primary teeth, dental follicles, and periodontal ligaments.2 Dental pulp should be only from healthy teeth, and ideally from donors younger than 30 years old because the cells lose their ability to regenerate. There are many potential applications for stem cell therapy in dentistry, and it holds promise for a wide range of clinical outcomes, although everything is still in at an in vitro experimental stage. The following are some noteworthy areas where stem cell therapy has shown potential in dentistry.3,4

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