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Sore or swollen lips part 1: causes and diagnosis

From Volume 43, Issue 9, November 2016 | Pages 874-882

Authors

Dimitrios Malamos

DDS, MSc, PhD, DipOM

Oral Medicine Clinic, National Organization for the Provision of Health Services (IKA), Athens, Greece

Articles by Dimitrios Malamos

Crispian Scully

CBE, DSc, DChD, DMed (HC), Dhc(multi), MD, PhD, PhD (HC), FMedSci, MDS, MRCS, BSc, FDS RCS, FDS RCPS, FFD RCSI, FDS RCSEd, FRCPath, FHEA

Bristol Dental Hospital, Lower Maudlin Street, Bristol BS1 2LY, UK

Articles by Crispian Scully

Abstract

This series of three papers reviews the causes, diagnosis and differential diagnosis, and outlines the management of sore and/or swollen lips.

CPD/Clinical Relevance: Sore and/or swollen lips are not uncommon, often have a local cause but may reflect a systemic disease. This first part of a series of three papers reviews their causes and diagnosis alphabetically, for ease of reference.

Article

The lips are important. They are frequently exposed to potentially harmful factors such as adverse weather conditions, hot, cold or other physical agents, caustic foods/drinks, allergens and micro-organisms.

Lesions on the lips can be disfiguring and of serious aesthetic concern to patients, and may herald usually local or sometimes systemic diseases. Some lesions are isolated, and some may be seen in association with other lesions in the oral mucosa, or in the skin, other mucosae (genitals, ocular), or elsewhere. Some are swollen or sore and some are both.

Lip inflammation (cheilitis) can be acute or chronic and appears within a few hours after lip exposure to various harmful agents and lasts from days to a few months or even years. Some cheilitis have a predilection for certain areas, such as the lip commissures (angular), the lower lip (chronic actinic; atopic; follicular and glandular), or the upper lip (granulomatous – initial stage), while others can occur anywhere (trauma, burns, herpes labialis, simplex, exfoliative, irritant and allergic contact, plasma cell and granulomatous – late stage) (Table 1). Lip diseases have been reviewed elsewhere,1,2 but additional information regarding their clinical forms, pathogenesis and treatment has accumulated over the last 15 years.

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