References

Larmour CJ, Mossey PA, Thind BS Hypodontia – a retrospective review of prevalence and etiology. Part I. Quintessence Int. 2005; 36:263-270
Pemberton TJ, Das P, Patel PI. Hypodontia: genetics and future perspectives. Braz J Oral Sci. 2005; 4
Rakhshan V. Congenitally missing teeth (hypodontia): a review of the literature concerning the etiology, prevalence, risk factors, patterns and treatment. Dent Res J (Isfahan). 2015; 12:1-13 https://doi.org/10.4103/1735-3327.150286
Mărgărit R, Andrei OC, Tănăsescu LA Non-syndromic familial hypodontia: rare case reports and literature review. Rom J Morphol Embryol. 2019; 60:1355-1360
AlShahrani I, Togoo RA, AlQarni MA. A review of hypodontia: classification, prevalence, etiology, associated anomalies, clinical implications and treatment options. World J Dent. 2013; 4:117-125
Vastardis H, Karimbux N, Guthua SW A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet. 1996; 13:417-421 https://doi.org/10.1038/ng0896-417
Stockton DW, Das P, Goldenberg M Mutation of PAX9 is associated with oligodontia. Nat Genet. 2000; 24:18-19 https://doi.org/10.1038/71634
Liu W, Wang H, Zhao S The novel gene locus for agenesis of permanent teeth (He-Zhao deficiency) maps to chromosome 10q11.2. J Dent Res. 2001; 80:1716-1720 https://doi.org/10.1177/00220345010800080701
Vieira AR, Meira R, Modesto A, Murray JC. MSX1, PAX9, and TGFA contribute to tooth agenesis in humans. J Dent Res. 2004; 83:723-727 https://doi.org/10.1177/154405910408300913
Callahan N, Modesto A, Meira R Axis inhibition protein 2 (AXIN2) polymorphisms and tooth agenesis. Arch Oral Biol. 2009; 54:45-49 https://doi.org/10.1016/j.archoralbio.2008.08.002
De Santis D, Sinigaglia S, Faccioni P Syndromes associated with dental agenesis. Minerva Stomatol. 2019; 68:42-56 https://doi.org/10.23736/S0026-4970.18.04129-8
Khalaf K, Miskelly J, Voge E, Macfarlane TV. Prevalence of hypodontia and associated factors: a systematic review and meta-analysis. J Orthod. 2014; 41:299-316 https://doi.org/10.1179/1465313314Y.0000000116
Gokay GD, Durkan R, Oyar P. Evaluation of physical properties of polyamide and methacrylate based denture base resins polymerized by different techniques. Niger J Clin Pract. 2021; 24:1835-1840 https://doi.org/10.4103/njcp.njcp_469_20
Goya HA, Tanaka S, Maeda T, Akimoto Y. An orthopantomographic study of hypodontia in permanent teeth of Japanese pediatric patients. J Oral Sci. 2008; 50:143-150 https://doi.org/10.2334/josnusd.50.143
Pirinen S, Arte S, Apajalahti S. Palatal displacement of canine is genetic and related to congenital absence of teeth. J Dent Res. 1996; 75:1742-1746 https://doi.org/10.1177/00220345960750100601
Simon T, Nwabueze I, Oueis H, Stenger J. Space maintenance in the primary and mixed dentitions. J Mich Dent Assoc. 2012; 94:38-40
Guo TW, Xing HL, Wang J, Wang BC. [Summary of 61 cases of removable denture restoration in children with congenital tooth deficiency]. Shanghai Kou Qiang Yi Xue. 2019; 28:196-200
Love RJ, Murray JM, Mamandras AH. Facial growth in males 16 to 20 years of age. Am J Orthod Dentofacial Orthop. 1990; 97:200-206 https://doi.org/10.1016/S0889-5406(05)80052-6
Bohner L, Hanisch M, Kleinheinz J, Jung S. Dental implants in growing patients: a systematic review. Br J Oral Maxillofac Surg. 2019; 57:397-406 https://doi.org/10.1016/j.bjoms.2019.04.011

Case report of an Afro-Caribbean adolescent with moderate hypodontia managed with a partial flexible denture

From Volume 50, Issue 4, April 2023 | Pages 275-277

Authors

Shaun Ramlogan

DDS (UWI), MSc (EDI, UCL), MClinDent (EDI, UCL), MFDS RCS Ed

Lecturer in Periodontology; Restorative Unit, School of Dentistry, University of the West Indies, St Augustine, Trinidad and Tobago, West Indies

Articles by Shaun Ramlogan

Email Shaun Ramlogan

Vidya Raman

DDS (UWI), DPDS (Bristol), MScD (Cardiff), MHEd (UWI)

Lecturer in Periodontology; Restorative Unit, School of Dentistry, University of the West Indies, St Augustine, Trinidad and Tobago, West Indies

Articles by Vidya Raman

Abstract

A 14-year-old male of Afro-Caribbean descent presented with moderate hypodontia, missing some of the permanent mandibular premolars and the lower central incisors, which was a rare finding. There were no apparent associated systemic or syndromic relationships. The main dental concerns were aesthetics, function and space maintenance until adolescent craniofacial bone growth had ceased. Thus, an initial intervention entailed provision of a unilateral removable partial flexible denture that was acceptable to the patient and provided a suitable aesthetic result for the young person. This approach was preferred to a ‘band and loop’ appliance proposed in the literature because the removable partial denture supported function and aesthetics.

CPD/Clinical Relevance: Unilateral removable partial flexible dentures may be useful in mid-adolescent cases of hypodontia.

Article

Congenitally missing teeth, or agenesis of teeth, refers to the lack of development and oral presentation of teeth as determined clinically and radiographically. Various classifications have been proposed in the literature, with hypodontia being defined as few teeth absent (<6 teeth, excluding the third molars), oligodontia or severe hypodontia defined as many teeth absent (≥6 teeth, excluding the third molars) and anodontia defined as the complete absence of teeth.1,2,3,4 Further classifications of hypodontia include mild hypodontia representing fewer than three missing teeth and moderate hypodontia with fewer than six missing teeth have been also suggested.5

The tooth development stage may be affected by many genetic factors. The commonly cited genes associated with teeth agenesis include MSX1, PAX9, TGFA, AXIN2, and potentially a locus on chromosome 10.6,7,8,9,10 Congenitally missing teeth may be either non-syndromic or syndromic, with the most commonly reported conditions being Down syndrome, ectodermal dysplasia and labio-palatal clefts.11

Register now to continue reading

Thank you for visiting Dental Update and reading some of our resources. To read more, please register today. You’ll enjoy the following great benefits:

What's included

  • Up to 2 free articles per month
  • New content available