Focal Palmoplantar and Gingival Hyperkeratosis: A Case Report

From Volume 34, Issue 5, June 2007 | Pages 290-294

Authors

Jadbinder Seehra

BDS(Hons), MFDS, MSc, MOrth, FDS

Senior House Officer, Unit of Oral Medicine, The School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK

Articles by Jadbinder Seehra

Nalin Thakker

BDS, MSc, PhD, FRCPath

Professor of Molecular Pathology and Genetics/Consultant Oral Pathologist, The School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK

Articles by Nalin Thakker

A John Duxbury

BDS, MSc, PhD, DDS, FDS RCPS, FDS RCS

Consultant/Honorary Senior Lecturer in Oral Medicine, The School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK

Articles by A John Duxbury

Philip Sloan

BDS, PhD, FDS RCS(Eng), FRCPath

Professor of Experimental Oral Pathology, The School of Dentistry, University of Manchester, Higher Cambridge Street, Manchester, M15 6FH, UK

Articles by Philip Sloan

Senathirajah Ariyaratnam

BDS, MDS, FDS RCS

Clinical Teacher (PT), Specialist in Oral Medicine

Articles by Senathirajah Ariyaratnam

Abstract

We report a rare genetic condition characterized by gingival hyperkeratosis with skin changes affecting the hands and feet. The patient presented with asymptomatic oral lesions and the diagnosis was reached by taking a full clinical history and biopsy tests. Palmoplantar keratosis can be a feature of a range of different syndromes and can be associated with periodontal destruction, benign oral keratosis or cancer of the oesophagus. It is important for dentists to be aware that clues to diagnosis can be gained from examination of the hands and feet, in addition to an oral examination, particularly in recognizing oral genetic disorders.

Article