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Bilateral dentigerous cysts: an updated literature review and report of a case with associated root resorption
From Volume 45, Issue 11, December 2018 | Pages 1063-1082
Article
A dentigerous cyst is an epithelial-lined cavity which surrounds the crown of an unerupted tooth at the cemento-enamel junction.1, 2 It is considered benign and is developmental in nature.3 Dentigerous cysts are the second most common odontogenic cysts following radicular cysts,4 with evidence suggesting that they account for 25% of all odontogenic cysts.5
Dentigerous cysts develop due to the accumulation of fluid between the reduced enamel epithelium and enamel of an unerupted tooth or within the enamel organ.6 The erupting tooth exerts pressure on the impacted follicle which obstructs venous outflow. This results in a serum transudate across the capillary wall causing elevated hydrostatic pressure and therefore pooling of fluid. This causes separation of the follicle from the crown, leading to formation of the cyst.6, 7 Given this mechanism, dentigerous cysts generally materialize during tooth development in young patients, with peak incidence in the second to fourth decades of life.3 The teeth most frequently associated with such cysts are mandibular third molars, followed by maxillary canines.4
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