Abstracts

The management of immature permanent teeth with a necrotic pulp has always been a challenge within the field of endodontics. Teeth with incomplete root development have short roots with thin root walls predisposing them to a high risk of fracture. Regenerative Endodontic Therapy (RET) has been proposed to facilitate root development in immature teeth with necrotic pulps and has the capacity to overcome the limitations of conventional endodontic treatment in these teeth.

This review critically appraised the literature on using RET and assessed clinical and radiographic outcomes. The authors searched a variety of electronic databases for English language studies, however, the search terms were not specified, nor were the specifics on study selection. Study quality was assessed independently by two reviewers. Fourteen studies were included (5 RCTs, 2 cohorts, 1 case-control and 6 uncontrolled prospective studies). Meta-analyses using a random effects model were performed to combine the results of the 5 RCTs.