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Article: Volume 48 Number 9 Page 726 - October 2021

  Dent Update 2021; 48: 726-730  Read article

Oral surgery:  Osteogenesis imperfecta: minimizing complications in oral surgery/orthodontic treatment

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Abstract: Osteogenesis imperfecta (OI) is a rare genetic condition that affects connective tissue and is primarily characterized by bone fragility. Owing to the progressive nature of the disease, patients require life-long management of the adverse effects and the subsequent complications they can experience. Since the introduction of bisphosphonates as a treatment modality, complications and bone deformities associated with OI have been minimized. However, intravenous bisphosphonates in young patients could present a new era of difficulties for the dental profession. We report on a case of a patient with OI who presented with severe orthodontic crowding and describe the multidisciplinary treatment planning required to minimize potential complications.

Clinical relevance: General dental practitioners should be aware of the characteristics of osteogenesis imperfecta and the potential complications associated with dental treatment.

Author notes: Kaye Jordan, BDS, Sheffield University. Emily Carter, BDS, MFDS RCSEd, Dip Con Sed, CILT, AFHEA, MOS RCSEd, The Royal London Hospital. Ciarán P Devine, BDentSc, MFD(RCSI), StR in Orthodontics, Royal London and Whipps Cross Hospital. Aliki Tsichlaki, MRes, MJDF, MOrth RCS Eng, FDSRCS (Orth), FHEA, Consultant in Orthodontics, The Royal London Hospital. Judith Jones, BDS, MSc, FDSRCS (Eng), PhD, FDS (OS), FHEA, Consultant in Oral Surgery, The Royal London Hospital. email: kaye.jordan@nhs.net

Objective: To update the reader on the management of patients with OI and the potential risks of dental treatment for patients with OI who are undergoing bisphosphonate therapy.

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