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Article: Volume 44 Number 7 Page 674 - July/August 2017

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  Dent Update 2017; 44: 674-678

Oral surgery:  Post-transplant Kaposi’s Sarcoma: An Unusual Presentation and Review of Clinical Presentation, Histology and Management

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Abstract: Kaposi’s sarcoma is an uncommon, vascular neoplasm associated with Human Herpes Virus 8 (HHV-8). An unusual case of PT-KS, presenting with pain from bilateral macular lesions on the palate, is discussed. As far as the authors are aware, this is the only reported case of a macular post-transplant Kaposi’s sarcoma initially presenting with pain. The diagnosis, clinical presentation and histology are discussed, and an update on the oral presentation and management of post-transplant Kaposi’s sarcoma is provided.

Clinical relevance: Post-transplant Kaposi’s sarcoma is a neoplasm found in post-transplant patients that can present intra-orally, and needs to be identified early to ensure the best possible outcome for the patient.

Author notes: Laura Whitehouse, BDS, Specialty Dentist in Oral Medicine, Bristol Dental Hospital, Lower Maudlin Street, Bristol, Miranda Pring, BSc(Hons), BDS, MFDS RCPS, PhD, FRCPath, Consultant in Oral and Maxillofacial Pathology, Bristol Royal Infirmary, Upper Maudlin Street, Robert Przemioslo, MD FRCP, Consultant in Gastroenterology, Southmead Hospital, Southmead Way and Konrad S Staines, BChD, MOMED RCS(Edin), FDS RCS(Eng), Consultant in Oral Medicine, Bristol Dental Hospital, Lower Maudlin Street, Bristol, UK.

Objective: To recognize the clinical and histological appearances of Kaposi’s sarcoma and understand the management required for this neoplasm.