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Article: Volume 43 Number 3 Page 267 - April 2016

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  Dent Update 2016; 43: 267-271

Oral medicine:  Return of the Great Pox

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Abstract: Syphilis is on the increase globally. While recognized more frequently in patients with, HIV/AIDS, it is not unusual among immune competent individuals sometimes presenting with unusual manifestations and/or behaviour. This paper reviews the history and clinical features of syphilis and draws attention to the oral manifestations.

Clinical relevance: Syphilis should be in the differential diagnosis of oral ulcers or unusual oral lesions.

Author notes: Crispian Scully, CBE, MD, PhD, MDS, MRCS, BSc, FDS RCS, FDS RCPS, FFD RCSI, FDS RCSE, FRCPath, FMedSci, FHEA, FUCL, FSB, DSc, DChD, DMed(HC), DrHC, WHO Collaborating Center for Oral Health-General Health; and University College London, UK and Jane F Setterfield, MD, BDS, DCH, FRCP, Mucosal and Salivary Biology Division, Dental Institute, King’s College London and St John’s Institute of Dermatology, Guy’s and St Thomas’s NHS Foundation Trust, London, UK.

Objective: To recognize syphilis in the differential diagnosis of oral ulcers or unusual oral lesions.