Article: Volume 48 Number 5 Page 379 - May 2021

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  Dent Update 2021; 48: 379-382

Oral medicine:  Stressful life events as a trigger for autoimmune disease? A case report on mucous membrane pemphigoid

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Abstract: This case discusses the acute presentation of a patient with mucous membrane pemphigoid to an emergency dental department. Mucous membrane pemphigoid is a rare condition, but its presentation can be severe and concerning for both the patient and clinician. The case presents the manifestations of florid desquamative gingivitis and extensive mucosal erosions due to burst bullae. We discuss the possible causes of the condition in this patient, likely to be the stress of recent cardiac surgery, as well as exploring the efficacy of diagnostic tools, treatment options and adverse effects of corticosteroid treatment.

Clinical relevance: Correct and timely diagnosis of vesiculobullous disorders has notable impacts on patient outcomes and quality of life.

Author notes: Robert Devine, BDS (QMUL), MJDF, Dental Core Trainee in Oral and Maxillofacial Surgery, Royal United Hospitals, Bath. Melanie Simms, BDS, MFDS RCPS(Glasg), PGCert (Dent Ed), Specialist Registrar in Oral Medicine, University Dental Hospital, Cardiff. email:

Objective: The reader should understand the clinical presentation of mucous membrane pemphigoid in order to facilitate timely referral and communication between dental and medical specialities.