Article: Volume 46 Number 7 Page 672 - July/August 2019

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  Dent Update 2019; 46: 672-674

Oral and Maxillofacial Surgery:  Primary B-Cell Lymphoma of the Mandible: a Potentially Difficult Diagnosis

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Abstract: There are many causes of a persistent unilateral numbness of the lower lip. A case report of a 34-year-old normally fit and well male, whose symptoms of numbness of the mandibular division of the right trigeminal nerve represented the rare diagnosis of a primary B-cell lymphoma of the mandible, is presented here. The patient’s presentation and management, reasons for the difficulty in ascertaining a definitive diagnosis, as well as invaluable points to be reflected on from this case, are discussed.

Clinical relevance: Numbness should be treated with a high degree of suspicion, with urgent imaging, biopsy and specialist histopathology staining being carried out to exclude malignancy.

Author notes: Hudson King, BDS(Hons), MFDS RCPS(Glasg), Dental Core Trainee Level 2, Liverpool University Dental Hospital (email: and Simon Rogers, BDS, MBChB(Hons), FDS RCS(Eng), FRCS(Eng), FRCS(Max), MD, Consultant Oral and Maxillofacial Surgeon, Aintree University Hospital, Liverpool L9 7AL, UK.

Objective: To describe an unusual clinical presentation of a primary B-cell lymphoma of the mandible and demonstrate the importance of a biopsy in establishing diagnosis.