Article: Volume 46 Number 7 Page 634 - July/August 2019

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  Dent Update 2019; 46: 634-644

Special Care Dentistry:  Ehlers-Danlos Syndrome: a Review

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Abstract: Ehlers-Danlos Syndrome (EDS) affects the metabolism of collagen which can have implications throughout the body, impacting on not only the skin, but also the joints, muscles, cardiovascular and gastrointestinal systems. The condition can have dental implications such as poor wound healing, mucosal fragility, prolonged bleeding, temporomandibular joint dislocation and, in some forms, periodontal disease. Three clinical cases of patients with EDS will be discussed and their dental management described. The patient with EDS may be seen in primary care and, if input from secondary care is required, a multidisciplinary, shared care approach will ideally be utilized.

Clinical relevance: Ehlers-Danlos Syndrome is a condition that can be multifactorial, with medical implications as well as dental; depending on the manifestations of the condition, the patient may be seen in primary and/or secondary care with or without a shared care approach.

Author notes: Samina Nayani, BDS(Hons), MFDS RCSEd, Specialty Registrar in Special Care Dentistry, King’s College Hospital (email:, Joanna Dick, BDS, MJDF RCSEng, DipDSed, Specialty Registrar in Special Care Dentistry, The Royal London Dental Hospital, Turner Street, Whitechapel, London E1 1BB and Charlotte Curl, BDS(Hons), FDS RCS(Eng) DSCD RCS(Eng), PgDipClinEd FHEA, Consultant in Special Care Dentistry, Department of Community and Special Care Dentistry, King’s College Hospital, Denmark Hill, London SE5 9RS, UK.

Objective: To provide guidance for GDPs to deliver safe and effective treatment for Ehlers-Danlos syndrome.