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Article: Volume 41 Number 7 Page 613 - September 2014

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  Dent Update 2014; 41: 613-622

Oral and Maxillofacial Surgery:  Bone Defects of the Jaws: Moving from Reconstruction to Regeneration

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Abstract: Jaw reconstruction is necessary for a variety of reasons including neoplastic disease, traumatic injuries, infective/inflammatory lesions, and congenital defects. Such defects can be a significant handicap for patients leading to physiological and psychological morbidity. Maxillofacial bone reconstruction remains challenging for the reconstructive surgeon; yet it has evolved significantly over recent years. The current state of the art reconstruction is via the use of vascularized osseous flaps. Modern developments in regenerative medicine propose a future for stem cells in the regeneration of bone for jaw defects.

Clinical relevance: Knowledge of the current methods of reconstruction and advances in the field of tissue engineering is of interest to dental clinicians.

Author notes: Elena Kyriakidou, BDS, MFDS RCS(Edin), MClinDent in Oral Surgery, Academic Clinical Fellow/Specialty Trainee in Oral Surgery, School of Clinical Dentistry, University of Sheffield, Norma O’Connor, BDS, MFDS RCS(Edin), MClinDent in Oral Surgery, MOral Surg, Specialty trainee in Oral Surgery, Edinburgh Dental Institute, Nicholas J Malden, FDS, DDS, Consultant in Oral Surgery, Edinburgh Dental Institute and Victor R Lopes, FRCS, PhD, Professor of the Combined Department of Oral and Maxillofacial Surgery and Oral Medicine, Edinburgh Dental Institute and St John’s Hospital, Livingston, UK.

Objective: To describe the current reconstructive techniques available for reconstruction of maxillofacial bone defects.