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Ehlers-Danlos Syndrome (EDS) affects the metabolism of collagen which can have implications throughout the body, impacting on not only the skin, but also the joints, muscles, cardiovascular and gastrointestinal systems. The condition can have dental implications such as poor wound healing, mucosal fragility, prolonged bleeding, temporomandibular joint dislocation and, in some forms, periodontal disease. Three clinical cases of patients with EDS will be discussed and their dental management described. The patient with EDS may be seen in primary care and, if input from secondary care is required, a multidisciplinary, shared care approach will ideally be utilized.
CPD/Clinical Relevance: Ehlers-Danlos Syndrome is a condition that can be multifactorial, with medical implications as well as dental; depending on the manifestations of the condition, the patient may be seen in primary and/or secondary care with or without a shared care approach.
Article
Ehlers Danlos Syndrome (EDS) is a rare syndrome characterized by 13 types of connective tissue disorders which manifest primarily in dermatological and joint conditions. EDS affects collagen metabolism, leading to deficiency and/or disordered deposition of collagen.1 Within the literature there is an overlap between the EDS subtypes and other connective tissue diseases, including hypermobility disorders, for example Joint Hypermobility Syndrome (JHS), which is often referred to interchangeably with EDS.2
The condition was first described in 1657 when a young Spanish man was found to be able to stretch the skin overlying his right pectoral muscle over the left angle of his mandible.3 Further descriptors were added in 1901 by Ehlers, 1908 by Danlos, and then by Poumeau-Delille and Soulie in 1934 when the condition was described as Ehlers-Danlos Syndrome.4
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