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Article: Volume 45 Number 1 Page 64 - January 2018

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  Dent Update 2018; 45: 64-70

Paediatric dentistry:  Hypophosphatasia: Diagnostic Clues for the Dental Practitioner

CPD:  CPD  0:24   (closes in 16 days)

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Abstract: Hypophosphatasia has a wide clinical spectrum ranging from premature loss of primary teeth to neonatal death. The premature loss of primary teeth in a child with an otherwise unremarkable history may be the first sign of a more significant underlying disease. This report illustrates the role of the dental practitioner in facilitating the diagnosis of hypophosphatasia.

Clinical relevance: This report outlines the signs and symptoms essential to facilitate the diagnosis of hypophosphatasia by the dental practitioner.

Author notes: Jilen Patel, BDSc(Hons) UWA, FADI, Paediatric Dental Registrar, Robert P Anthonappa, BDS, MDS(Paed Dent), AdvDipDS, PhD, MPaedDent RCSEd, FDS RCSEd, MRACDS(Paed), Discipline Lead and Program Convenor, Paediatric Dentistry and Nigel M King, BDS(Hons), MSc(Hons), FDS RCSEd, FDS RCS(Eng), LDS RCS, PhD, Professor of Paediatric Dentistry, School of Dentistry, The University of Western Australia, 17 Monash Avenue, Nedlands WA 6009 Australia.

Objective: To outline the signs and symptoms essential to facilitate the diagnosis of hypophosphatasia by the dental practitioner. Enhanced CPD DO C

ADG