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Returning to foundation principles: oral rehabilitation of a child with ectodermal dysplasia and hypodontia Nidhi Parmar Rajkaran Singh Virdi Dental Update 2025 52:1, 707-709.
Ectodermal dysplasias (ED) are a group of genetic disorders, of which common oral presentations include severe hypodontia and conically formed anterior dentition. With the average ED patient missing 23.7 permanent teeth, the ramifications of severe hypodontia directly correlate with quality of life and treatment complexities. The aim of prosthodontic rehabilitation is to provide an age-appropriate dentition to aid aesthetics, phonetics, masticatory and psychosocial development, recommended for commencement at an early age, including support throughout life. This case report demonstrates a non-invasive, simple and predictable approach to the prosthodontic rehabilitation of a 9-year-old child with ED affected by severe hypodontia.
CPD/Clinical Relevance: Non-surgical prosthetic treatment can be a safe and predictable first-line treatment for the oral rehabilitation in patients with hypodontia.
Article
Ectodermal dysplasia (ED) is the term defining over 150 rare, inherited syndromes, with genetic defects in two or more ectodermal structures such as skin, hair, nails, exocrine glands, sebaceous glands, and teeth.1 The notable phenotypic signs and symptoms on which an ED diagnosis is made includes hypohidrosis, hypotrichosis, and severe hypodontia of both primary and permanent dentitions.2 Severe hypodontia is the agenesis of six or more teeth, with the exclusion of third molars, and it is reported that children with ED have, on average, 23.7 missing permanent teeth.3,4 Since severe hypodontia leads to hypoplasia of the alveolar ridges, there is a subsequent reduction in occlusal vertical dimension and impact on the lower vertical face height. This compromises facial aesthetics resulting in distinctive appearances comparable to edentulous patients who have not been restored, owing to increased labial folding and prominence of the chin. It should be noted that 80% of patients with ED exhibit additional oral anomalies, such as xerostomia, delayed eruption, microdontia, irregular shaped or malformed dentition, which pose further treatment complications.5
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